Doctor Silver Ion began its academic research in 2004 with antiviral, antimicrobial, and antibacterial fabric technology. Researchcontinued in 2014 at Istanbul Technical University's Textile Engineering Faculty and ITU Technopark (technology developmentcenter), with a mission to develop innovative solutions by creating patentable technologies.Hippocrates Changersla R&D and Nano Technologies Inc. has developed and produced product and brand groups, includingDoktorsilverion-Silverionmask-Changersla, in the medical sector. These include healthcare products, surgical masks, and N99category masks developed for doctors and athletes using antiviral textile fabrics.